
Chemistry of Heterocyclic Compounds p. 796 - 801 (1998)
Update date:2022-07-29
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El-Sayed, Ragab A.
Thiophene-2-carboxanilide and its p-chloro and p-bromo derivatives react with chlorosulfonic acid to give the corresponding sulfonyl chlorides, which react with amino acids to give the respective derivatives. Several methyl esters of the latter were prepared. Hydrazinolysis of these methyl esters yielded the hydrazides. Coupling reactions of some sulfonylamino acids with amino acid methyl ester hydrochlorides in THF-Et3N medium using the dicyclohexylcarbodiimide method give the corresponding dipeptide methyl esters. The spectral data of the compounds are briefly discussed. 1999 Kluwer Academic/Plenum Publishers.
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Doi:10.1016/S0040-4039(98)00759-X
(1998)Doi:10.1021/jo980063o
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(1998)Doi:10.1248/cpb.60.647
(2012)Doi:10.1246/cl.2005.246
(2005)Doi:10.1080/10426509708043543
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