Syntheses of optically active 2-substituted cyclopropanecarboxylic acids from chiral α-hydroxysilane derivatives

DOI: 10.1016/S0040-4039(98)00759-X

Source and publish data:

Tetrahedron Letters p. 4311 - 4312 (1998)

Update date:2022-07-29

Topics:

Authors:

Sakaguchi, Kazuhiko

Mano, Hiroyuki

Ohfune, Yasufumi

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Article abstract of DOI:10.1016/S0040-4039(98)00759-X

Optically active 2-alkylcyclopropanecarboxylic acids were efficiently synthesized from the chiral α-hydroxytrimethylsilanes via a diastereoselective cyclopropanation as the key step.

Full text of DOI:10.1016/S0040-4039(98)00759-X

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Product name:Cyclopropanecarboxylic acid, 2-butyl-, methyl ester, (1R,2S)- (9CI)

Cas No:210546-52-4

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