Tetrahedron Letters p. 3749 - 3752 (1998)
Update date:2022-09-26
Topics:
Matsushita, Masayuki
Maeda, Hana
Kodama, Mitsuaki
An efficient route for the asymmetric synthesis of α,α-disubstituted α-amino acids derivatives (1, 2, and 3) starting from readily available epoxy silyl ethers (6) has been developed. High enantiomeric purity can be realized by the present method using a combination of MABR rearrangement of a chiral epoxide and Curtius rearrangement.
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Doi:10.1016/S0040-4039(98)00977-0
(1998)Doi:10.1016/S0040-4039(98)00991-5
(1998)Doi:10.1021/jo005698d
(2001)Doi:10.1139/v98-048
(1998)Doi:10.1016/S0040-4039(98)01123-X
(1998)Doi:10.7164/antibiotics.51.655
(1998)
