Extremely stereoselective alkylation of 3-siloxy-β-lactams and its applications to the asymmetric syntheses of novel 2-alkylisoserines, their dipeptides, and taxoids

DOI: 10.1016/S0040-4039(98)00643-1

Source and publish data:

Tetrahedron Letters p. 3663 - 3666 (1998)

Update date:2022-08-03

Topics:

Authors:

Ojima, Iwao

Wang, Tao

Delaloge, Francette

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Article abstract of DOI:10.1016/S0040-4039(98)00643-1

New and efficient synthetic mutes to 2-alkylisoserines, their dipeptides and 2'-alkyl-taxoids were synthesized from enantiopure 3-alkyl-β-lactams 3 which were obtained through extremely distereoselective alkylation of β- lactams 2.

Full text of DOI:10.1016/S0040-4039(98)00643-1

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