A straightforward preparation of chiral 5-(aminomethyl)oxazole derivatives from α-amino esters and α-lithiated isocyanides

DOI: 10.1248/cpb.46.860

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 860 - 862 (1998)

Update date:2022-08-04

Topics:

Authors:

Ohba, Masashi

Kubo, Hiroyuki

Seto, Shigeki

Fujii, Tozo

Ishibashi, Hiroyuki

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.46.860

An efficient and general preparation of several chiral N-protected 5- (aminomethyl)oxazoles has been accomplished by treatment of N-protected α- amino esters with α-lithiated isocyanides, obtained by metalation of methyl and benzyl isocyanides with BuLi or of ethyl isocyanide with lithium diisopropylamide.

Full text of DOI:10.1248/cpb.46.860

NII-Electronic Library Service

Products guided by the article

Product name:Carbamic acid, [1-(5-oxazolyl)ethenyl]-, 1,1-dimethylethyl ester (9CI)

Cas No:209589-51-5

R&D Labs maybe for 209589-51-5

SHIJIAZHUANG AGERUO-BIOTECH CO.LTD

Contact:+86-130-2866-6699

Address:Huaian east Road 158
Zhejiang kehong chemical co., ltd

Contact:0086-575-85522000

Address:xiner center RD binhai industrial zone shaoxing zhejiang province P.R.China,312073
Okeanos Tech.Co.,LTD

Contact:+86-10-62651721

Address:29 Yongxing Road, Daxing District,Beijing China
Taizhou YOJOY Chemical Co., Ltd.

Contact:13857143241

Address:Yangfu Industrial Park, Xianju, Zhejiang, P. R. China
qingdao goldenchem imp and exp co.,ltd.

Contact:532-55579246

Address:no.62 ,haier road laoshan distirct

Relevant to this article

Alkoxymesitylchlorogermanes and aryloxymesitylchlorogermanes

Doi:10.1016/S0020-1693(97)06137-9
(1998)
1-Aminocylopropane-1-carboxylic acid derivatives as ligands at the glycine-binding site of the N-methyl-D-aspartate receptor

Doi:10.1016/S0014-827X(98)00005-6
(1998)
Synthesis and Antiviral Evaluation of 1-[(2-Phenoxyethyl)oxymethyl] and 6-(3,5-Dimethoxybenzyl) Analogues of HIV Drugs Emivirine and TNK-651

Doi:10.1055/s-0035-1559683
(2016)
Design, Synthesis, Structure-Activity Relationship Studies, and Three-Dimensional Quantitative Structure-Activity Relationship (3D-QSAR) Modeling of a Series of O-Biphenyl Carbamates as Dual Modulators of Dopamine D3 Receptor and Fatty Acid Amide Hydrolase

Doi:10.1021/acs.jmedchem.6b01578
(2017)
Enantioselective synthesis of diamino dicarboxylic acids

Doi:10.1021/jo982034j
(1999)
Dioxouranium(VI) mixed ligand complexes containing 8-hydroxyquinoline and some amino acids

Doi:10.1080/00945719809351686
(1998)

Article Doi