Tetrahedron Letters p. 3627 - 3630 (1998)
Update date:2022-08-02
Topics:
Chen, Li
Sakai, Naomi
Moshiri, Sara T.
Matile, Stefan
In this model study toward supramolecular channels formed by oligonucleotide analogs, we describe the synthesis of hydrophobic guanine dimers 1 - 4. We found that the solubility of guanine dimers 1 - 4 is significantly reduced compared to hydrophobic (iso)guanosine monomers and independent of the nature of substituents at the exocyclic amine. This indicates that the (deoxy)ribose is important to form soluble, ionophoric G- quartets.
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Doi:10.1021/jm970847e
(1998)Doi:10.1055/s-1998-2055
(1998)Doi:10.1021/acs.orglett.0c01145
(2020)Doi:10.1211/0022357001777522
(2000)Doi:10.1021/ja01864a063
(1940)Doi:10.1021/om980158g
(1998)
