Total asymmetric synthesis of Seco-acids of 9,12 anhydroerythronolide aglycons

DOI: 10.1016/S0040-4039(98)00691-1

Source and publish data:

Tetrahedron Letters p. 4039 - 4042 (1998)

Update date:2022-08-04

Topics: Catalysts Chirality Carboxylic Acids Total asymmetric synthesis

Authors:

Ainge, Simon W.

Vogel, Pierre

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(98)00691-1

The Diels-Alder adduct of 2,4-dimethylfuran to 1-cyanovinyl (1'S)- camphanate was converted into (2R,3R,4S,5S,6R,7R)-3,6-epoxy-4,5- isopropylidenedioxy-2,4,6-trimethyl-7-[(tert-butyl)-dimethylsilylloxy]non-I- yl phenyl sulfoxides (6), the condensation of which with (3R,4S,5R,6S)-7- benzyloxy-3,5-isopropylidenedioxy-4,6-dimethylheptan-2-one (7) led to the partially-protected seco-acid of the 9,12-anhydroerythronolide aglycon (5).

Full text of DOI:10.1016/S0040-4039(98)00691-1

Products guided by the article

Product name:tert-Butyl-dimethyl-{(R)-1-[(3aR,4R,6R,6aS)-2,2,4,6a-tetramethyl-6-((S)-1-methyl-2-phenylsulfanyl-ethyl)-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl]-propoxy}-silane

Cas No:209855-04-9

R&D Labs maybe for 209855-04-9

Chengdu NoVi Biotechnology Co., Ltd.(expird)

Contact:13551243286/028-81458053

Address:NO.168-1-224 JULONG ROAD WUHOU DISTRICT, CHENGDU CITY,SICHUAN PROVINCE
Nanjing Norris Pharm Technology Co., Ltd.

Contact:+86-13901585132

Address:2 Qiande Road, Jiangning sciencepark Hi-Tech Zone, Nanjing, P.R.China
ZK Biochem Group Co., Ltd

Contact:+86-532-80762375

Address:No. 6, Hongkong Middle Road, Qingdao, China
Beijing Apis Biotechnology Co., Ltd.

Contact:86-010-67856775-8551

Address:NO.4PUHUANGYU ROAD,FENTAI DISTRICT, BEIJING, CHINA
Borun Chemical Co.,Ltd.

Contact:+86-574- 87178138; 87297407

Address:No. 809, Liudingxingzuo, cangsong road, Ningbo, China

Relevant to this article

Enantioselective Reaction of 2H-Azirines with Phosphite Using Chiral Bis(imidazoline)/Zinc(II) Catalysts

Doi:10.1002/anie.201704133
(2017)
Doi:10.1002/hlca.19360190141
(1936)
HYDROXYBENZOQUINONES FROM MYRSINACEAE PLANTS. I. RECONFIRMATION OF THE

Doi:10.1248/cpb.13.511
(1965)
New developments in asymmetric Bradsher cycloadditions: Use of chiral dienes

Doi:10.1016/S0040-4039(00)01708-1
(2000)
Synthesis of bis(diphenylphosphino) ethanenickel(II) organodichalcogenide complexes and cyclotrimerisation reaction of dimethylacetylenedicarboxylate : Structure of Ni(dppe) (SC₆H₄O)

Doi:10.1016/S0277-5387(97)00527-5
(1998)
Polyhalogenonitrobenzenes and derived compounds: Part 5. Improved preparations of 1,2,3,4-tetrafluoro-5,6-dinitrobenzene and 3,4,5,6-tetrafluoro-1,2-phenylenediamine, and the use of the latter for the synthesis of tetrafluorobenzheterocycles

Doi:10.1016/S0022-1139(96)03517-8
(1997)

Article Doi