The design and synthesis of N4-anthraniloyl-2'-dC, the improved syntheses of N4-carbamoyl- and N4-ureidocarbamoyl-2'-dC, incorporation into oligonucleotides and triplex formation testing

Article abstract of DOI:10.1080/07328319808004232

Three modified nucleosides were designed with the aim of achieving triplet formation with the CG base pair of duplex DNA. Direct anthraniloylation of 2'-deoxycytidine, using isatoic anhydride, afforded the novel N⁴-anthraniloyl-2'-deoxycytidine

Full text of DOI:10.1080/07328319808004232

Nucleosides and Nucleotides
ISSN: 0732-8311 (Print) (Online) Journal homepage: http://www.tandfonline.com/loi/lncn19
The Design and Synthesis of N 4-Anthraniloyl-2′-
dC, the Improved Syntheses of N 4-Carbamoyl-
and N4- Ureidocarbamoyl-2′-dC, Incorporation into
Oligonucleotides and Triplex Formation Testing
Nancy Guzzo-Pernell , Geoff W Tregear , Jim Haralambidis & John M Lawlor
To cite this article: Nancy Guzzo-Pernell , Geoff W Tregear , Jim Haralambidis & John M
Lawlor (1998) The Design and Synthesis of N 4-Anthraniloyl-2′-dC, the Improved Syntheses
of N 4-Carbamoyl-and N4- Ureidocarbamoyl-2′-dC, Incorporation into Oligonucleotides
and Triplex Formation Testing, Nucleosides and Nucleotides, 17:7, 1191-1207, DOI:
10.1080/07328319808004232
To link to this article: http://dx.doi.org/10.1080/07328319808004232
Published online: 21 Aug 2006.
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Date: 01 June 2016, At: 17:05