Tetrahedron Letters p. 5057 - 5060 (1998)
Update date:2022-08-03
Topics:
Tanaka, Fujie
Oda, Motoko
Fujii, Ikuo
A pyridoxal-mediated abzyme system for aldol and retro-aldol reaction is demonstrated. Antibody 10H2 catalyzes the aldol and retro-aldol reactions of 4-acetamidobenzaldehyde and glycine to β-hydroxy α-amino acid, using pyridoxal 5'-phosphate as a cofactor.
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Doi:10.1021/om400651p
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