Synthesis of spirolactams from tyrosine amides and related substances

DOI: 10.1016/S0040-4039(98)00874-0

Source and publish data:

Tetrahedron Letters p. 4667 - 4670 (1998)

Update date:2022-08-05

Topics:

Authors:

Braun, Norbert A.

Ciufolini, Marco A.

Peters, Karl

Peters, Eva-Maria

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Article abstract of DOI:10.1016/S0040-4039(98)00874-0

Oxidation of oxazolines derived from phenolic ω-arylalkanoic acids such as tyrosine with iodobenzene diacetate leads to spirocyclic amides in moderate yields. This reaction was heretofore unknown due to the propensity of free amide analogs of the oxazolin

Full text of DOI:10.1016/S0040-4039(98)00874-0

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