A synthesis of 4-thiomethylbenzisothiazolone-1,1-dioxide using HDPT

DOI: 10.1016/S0040-4039(98)01074-0

Source and publish data:

Tetrahedron Letters p. 5309 - 5312 (1998)

Update date:2022-08-04

Topics:

Authors:

Yeung, Kap-Sun

Meanwell, Nicholas A.

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Article abstract of DOI:10.1016/S0040-4039(98)01074-0

4-Thiomethylbenzisothiazolone-1,1-dioxides were synthesized via the corresponding 4-methylbenzisothiazolone-1,1-dioxides by a regioselective benzylic bromination, followed by conversion of the bromide to the thiol moiety under mild and neutral reaction co

Full text of DOI:10.1016/S0040-4039(98)01074-0

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Product name:4-(4-Chloro-benzenesulfonyl)-benzoic acid 4-bromomethyl-1,1,3-trioxo-1,3-dihydro-1λ⁶-benzo[d]isothiazol-2-ylmethyl ester

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