Tetrahedron p. 8745 - 8752 (1998)
Update date:2022-08-02
Topics:
Girard
Demaison
Lee
Agrofoglio
Synthesis of hitherto unknown carbocyclic α-L-isomeric homonucleosides (8a-b, 9a-b) is described. The key intermediate 6 was synthesized from the known compound 1 as a chiral starting material. Construction of the heterocyclic moiety around the amino group of 6 afforded carbocyclic α-L- isomeric 2',3'-dideoxyhomonucleosides 8a-b and their 2',3'-didehydro-2',3'- dideoxy derivatives 9a-b.
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Doi:10.1021/acs.jmedchem.7b00708
(2017)Doi:10.1007/BF01142786
(1985)Doi:10.1002/mrc.1089
(2002)Doi:10.1021/om980162s
(1998)Doi:10.1021/op3000493
(2012)Doi:10.1016/S0040-4020(98)00511-0
(1998)