Second-Generation Trifluoromethyl-Substituted Chiral Dendrimers Containing Triply Branched Building Blocks: CF3 as Sensitive NMR Probe for 'Remote' Diastereotopicity

Article abstract of DOI:10.1002/hlca.19980810515

(S)-4,4,4-Trifluoro-3-hydroxybutanoic acid was used as a starting material for the synthesis of dendritic branches (16-21, 30-32) which were attached to a chiral triol (6 or ent-6), derived from (A)-3-hydroxybutanoic acid, to give CF₃-substitut