Tetrahedron Letters p. 5405 - 5408 (1998)
Update date:2022-08-02
Topics:
Khalafy, Jabbar
Svensson, Carina E.
Prager, Rolf H.
Williams, Craig M.
2-(1-Aminoalkyl)oxazole-4 and 5-carboxylates are available, without detectable racemisation, by a sequence involving N-acylation of isoxazol- 5(2H)one carboxylates with phthalimidoamino acids, photolysis of the acylated product, and hydrazinolysis. An application of the procedure to the synthesis of almazole A and B is described.
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Doi:10.1021/om980162s
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(2012)Doi:10.1016/S0040-4020(98)00511-0
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(2019)Doi:10.1016/S0968-0896(03)00061-0
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