Synthesis and applications of nonracemic β-amino aldehydes to the asymmetric synthesis of piperdines: (+)-Dihydropinidine

Article abstract of DOI:10.1016/S0040-4039(98)01223-4

New methodology for the enantioselective synthesis of stable N-protected β-amino aldehydes 5 and 6, and their application to the asymmetric synthesis of (+)-2-phenylpiperdine (11) and (+)-dihydropinidine (14) is described.