Conformational probes for elucidating the nature of substance P binding to the NK1 receptor: Initial efforts to map the Phe7-Phe8 region

Article abstract of DOI:10.1016/S0960-894X(98)00289-3

Three substance P analogs with conformation constraints in the Phe⁷- Phe⁸ region have been prepared in connection with an effort to differentiate two families of potential conformations for the binding of substance P to its NK_1<