Syntheses of 2-[(3,5-dimethyl-4-methoxypyridyl)alkyl]-benzothiazolidine derivatives as a potential gastric H+/K+-ATPase inhibitor

DOI: 10.1016/S0960-894X(98)00334-5

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Bioorganic and Medicinal Chemistry Letters p. 1909 - 1912 (1998)

Update date:2022-09-26

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Authors:

Yoon, Sung-Hwa

Seo, SeungKi

Lee, YoungHee

Hwang, SungKwan

Kim, Dong Yeon

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Article abstract of DOI:10.1016/S0960-894X(98)00334-5

A series of 2-[(3,5-dimethyl-4-methoxypyridyl)alkyl]benzothiazolidine derivatives were synthesized and tested their inhibitory effects on gastric H⁺/K⁺-ATPase. Compound 4d exhibited potent in vitro inhibitory activity.

Full text of DOI:10.1016/S0960-894X(98)00334-5

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