Stereoselective synthesis of alexine stereoisomers from (S)- pyroglutamic acid

DOI: 10.1016/S0040-4020(98)00542-0

Source and publish data:

Tetrahedron p. 8985 - 8998 (1998)

Update date:2022-08-05

Topics:

Authors:

Ikota, Nobuo

Nakagawa, Hidehiko

Ohno, Shigeru

Noguchi, Keiichi

Okuyama, Kenji

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Article abstract of DOI:10.1016/S0040-4020(98)00542-0

Four stereoisomers of alexine (1,7a-diepialexine (1a), 1,7,7a- triepialexine (1b), 1-epialexine (30a), and 1,7-diepialexine (30b)), the polyhydroxylaled pyrrolizidine alkaloid, were synthesized from (S)- pyroglutamic acid derivative (6).

Full text of DOI:10.1016/S0040-4020(98)00542-0

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