Selective deprotection strategies to N-(α-methylbenzyl)-β-amino esters and derived β-lactams

DOI: 10.1016/S0040-4039(98)01193-9

Source and publish data:

Tetrahedron Letters p. 6045 - 6048 (1998)

Update date:2022-08-04

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Authors:

Davies, Stephen G.

Ichihara, Osamu

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Article abstract of DOI:10.1016/S0040-4039(98)01193-9

A variety of N,N-diprotected β-amino esters, prepared by highly diastereoselective conjugate addition of chiral lithium amides, were selectively mono-deprotected under either reductive (hydrogenolysis) or oxidative (DDQ or CAN) conditions. Combined with t

Full text of DOI:10.1016/S0040-4039(98)01193-9

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