A significantly improved condition for cyclization of phenethylcarbamates to N-alkylated 3,4-dihydroisoquinolones

DOI: 10.1016/S0040-4039(98)01395-1

Source and publish data:

Tetrahedron Letters p. 6609 - 6612 (1998)

Update date:2022-08-04

Topics:

Authors:

Wang, Xiao-Jun

Tan, Jonathan

Grozinger, Karl

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Article abstract of DOI:10.1016/S0040-4039(98)01395-1

Secondary phenethylcarbamates undergo a Bischler-Napieralski cyclization promoted by phosphorus pentoxide in refluxing phosphorus oxychloride to afford N-alkylated 3,4-dihydroisoquinolones in high yields.

Full text of DOI:10.1016/S0040-4039(98)01395-1

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