Asymmetric synthesis of anti-convulsive drug (S)-Vigabatrin

DOI: 10.1016/S0040-4039(98)01324-0

Source and publish data:

Tetrahedron Letters p. 6415 - 6418 (1998)

Update date:2022-07-29

Topics:

Authors:

Chandrasekhar

Mohapatra, Suchismita

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Article abstract of DOI:10.1016/S0040-4039(98)01324-0

An asymmetric synthesis of fully protected (S)-Vigabatrin is described using Sharpless asymmetric aminohydroxylation and reductive elimination of α-oxyβ-amino carbonylhydrazone as key steps.

Full text of DOI:10.1016/S0040-4039(98)01324-0

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