Mixed-backbone oligonucleotides containing segments of deoxynucleosides phosphorothioate and 2'-O-methylribonucleosides methylphosphonate: Synthesis and properties

Article abstract of DOI:10.1080/10426509908546256

Synthesis of mixed-backbone oligonucleotides containing segments of deoxynucleoside phosphorothioate and 2'-O-methylribonucleoSide methylphosphonate have been achieved by using N-Pent-4-enoyl (PNT) helerocyclic base-protected 2'-O-methylribonucleoside met