Chiral sulfoxide controlled asymmetric additions to C-N double bond. An efficient approach to stereochemically defined α-fluoroalkyl amino compounds

Article abstract of DOI:10.1016/S0040-4020(98)00779-0

This paper presents a full account of studies into the asymmetric addition reactions between α-lithium derivatives of enantiomerically pure methyl and benzyl p-tolyl sulfoxides and the N-(p-methoxyphenyl)aldimines, bearing trifluoromethyl, pentafluoroethy