6-N-(N-methylanthranylamido)-4-oxo-hexanoic acid : A new fluorescent protecting group applicable to a new DNA sequencing method

Article abstract of DOI:10.1080/07328319808004742

6-Amino-4-oxo-hexanoic acid with a fluorescent probe attached to the amino function, derivative of the levulinic acid has been developed for protection of hydroxyl groups. It is introduced by reaction of its symetrical anhydride and rapidly removed under mild conditions using a hydrazine- pyridinium acetate buffer at near neutral pH and room temperature. It can be used within the scope of a new DNA sequencing method and as a sensitive detectable protecting group.

Full text of DOI:10.1080/07328319808004742

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Nucleosides and Nucleotides
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6-N-(N-Methylanthranylamido)-4-Oxo-
Hexanoic Acid: A New Fluorescent
Protecting Group Applicable To A New
Dna Sequencing Method
Isabelle Rasolonjatovo a & Simon R. Sarfati a
a Unite de Chimie Organique, ERS 558, Institut Pasteur , 28 rue du Dr
Roux, 75724, Paris, France
Published online: 22 Aug 2006.
To cite this article: Isabelle Rasolonjatovo & Simon R. Sarfati (1998) 6-N-(N-Methylanthranylamido)-4-
Oxo-Hexanoic Acid: A New Fluorescent Protecting Group Applicable To A New Dna Sequencing Method,
Nucleosides and Nucleotides, 17:9-11, 2021-2025, DOI: 10.1080/07328319808004742
To link to this article: http://dx.doi.org/10.1080/07328319808004742
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