A synthetic approach towards the aromatic macrocyclic core of diazonamide a based on sp2-sp2 coupling protocols

DOI: 10.1016/S0040-4039(98)01819-X

Source and publish data:

Tetrahedron Letters p. 8167 - 8170 (1998)

Update date:2022-08-04

Topics:

Authors:

Boto, Alicia

Ling, Matthew

Meek, Graham

Pattenden, Gerald

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Article abstract of DOI:10.1016/S0040-4039(98)01819-X

The scope for a range of sp²-sp² coupling protocols to elaborate the phenyl-indole, indoleoxazole, oxazole-oxazole, and quaternary carbon units in the marine natural product diazonamide A 1 are described, leading to the synthesis of the benzofuran oxazoles 11a and 18, the benzofuran/biphenyl/indole 16, and the indole-bis-oxazole 25.

Full text of DOI:10.1016/S0040-4039(98)01819-X

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