
Nucleosides and Nucleotides p. 2175 - 2187 (1998)
Update date:2022-07-29
Topics:
Da Silva, Adilson D.
Maria, Edmilson Jose
Blanchard, Pierre
Fourrey, Jean-Louis
Robert-Gero, Malka
An approach to an asymmetric synthesis of carbocyclic sinefungin (cSF) 2 is proposed. The sequence, which uses an original radical based chemistry for C-C bond formation, led to the immediate precursor 18 of the protected desired compound. While the overall yield is modest, it is noticeable that only a limited number of steps are needed to obtain the target compound.
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