Diastereoselective synthesis of the model insect antifeedants related to azadiradione and epoxyazadiradione based on intramolecular insertion of α- aryl-α-diazoketones

Article abstract of DOI:10.1016/S0040-4020(98)00939-9

A new practical and stereoselective method for the synthesis of the model insect antifeedant CDE fragment of azadiradione and epoxyazadiradione, based on intramolecular insertion of α-aryl-α-diazoketones, has been developed. The procedure can be applied to complex systems. A short SAR study is reported.