Synthesis and biological activities of [N-MeLeu5]- and [N-MePhe5]- didemnin B

DOI: 10.1016/S0040-4020(98)01042-4

Source and publish data:

Tetrahedron p. 313 - 334 (1999)

Update date:2022-08-04

Topics:

Authors:

Pfizenmayer, Amy J.

Ramanjulu, Joshi M.

Vera, Matthew D.

Ding, Xiaobin

Xiao, Dong

Chen, Wei-Chuan

Joullie, Madeleine M.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(98)01042-4

Based on information from X-ray, NMR, and SAR data, the N,O-diMeTyr⁵ unit of didemnin B was believed to be important for biological activity. To determine the importance of aromaticity and the role of the methoxy group in this unit, two analogs

Full text of DOI:10.1016/S0040-4020(98)01042-4

Products guided by the article

Product name:cyclo--5-methylheptanoyl>oxy-3-(methoxymethoxy)-2,5-dimethylhexanoyl>-L-leucyl>-L-prolyl-N-methyl-L-phenylalanyl>-L-threonyl>

Cas No:220657-26-1

R&D Labs maybe for 220657-26-1

Beijing Mediking Biopharm Co., Ltd.

Contact:+86-10-89753524/81760121/81769521

Address:Hongxianghong Incubator, Beiqijia Town, Changping district, Beijing, China
JIANGXI AIFEIMU TECHNOLOGY CO.，LTD

Contact:+86-570-6040289

Address:FINECHEMICAL PARK,ZIBU TOWN,WANNIAN COUNTY,JIANGXI PROV.,CHINA,ZIP
HOST COUNTRY LIMITED

Contact:+852 83038667

Address:Room 1502, 15th Floor, SPA Centre,53-55 Lockhart Road, Wanchai, Hong Kong
KA-SHING Business Trade Macau Co., Ltd.

Contact:00853-28430045

Address:23rd Floor, Block 3 La Cite, Areia Preta, Macao

Relevant to this article

The reaction of phenylchlorophosphino-substituted 1,2-dicarba-closo-dodecaboranes(12) with elemental sulfur and molecular structures of rac-1,2-bis(phenylchlorophosphino)-1,2-dicarba-closo-dodecaborane(12) and 1-phenylchlorothiophosphino-2-phenyl-1,2-dicarba-closo-dodecaborane(12)

Doi:10.1016/S0277-5387(98)00330-1
(1998)
Synthesis and biological evaluation of 2',3'-didehydro-2',3'-dideoxy-5- fluorocytidine (D4FC) analogues: Discovery of carbocyclic nucleoside triphosphates with potent inhibitory activity against HIV-1 reverse transcriptase

Doi:10.1021/jm980510s
(1999)
Doi:10.1016/S0040-4039(01)99131-2
(1968)
Rat liver microsomal enzyme catalyzed oxidation of 1-cyclopropyl-4-phenyl-1,2,3,6-tetrahydropyridine

Doi:10.1016/S0968-0896(98)80027-8
(1998)
Doi:10.1007/BF00486949
()
An efficient catalyst free synthesis of nitrogen containing spiro heterocycles via [5 + 1] double Michael addition reaction

Doi:10.1039/c4ra00521j
(2014)

Article Doi