Bioorganic and medicinal chemistry letters p. 69 - 74 (1999)
Update date:2022-07-30
Topics:
Shih, Chuan
Gossett, Lynn S.
Gruber, Joseph M.
Grossman, C. Sue
Andis, Sherri L.
et al.
Structure modification of the β-alanine region (fragment C) of the potent antimitotic agent cryptophycin was investigated. This includes: (1) introduction of substituents at the previously unsubstituted C7 position of the macrolide ring and (2) replacement of the (2R)-3-amino-2-methyl-propanoic acid (β-alanine) with various (l)-amino acids to give the corresponding 15-membered unnatural cryptophycin analogs.
View MoreTianjin Tensing Fine Chemical Research Develop Centre
Contact:86-022-23718576,13032267585
Address:2-2-201,13 Guiyuan road,Huayuan Industry district,Tianjin,china
Shenzhen Regent Biochemistry Tech Co., Ltd.
website:http://shop.regentsciences.com/
Contact:+86-755-85201366
Address:PINGSHAN DIS., BAOSHAN INDUSTRIAL AREA
Heliosense Biotechnologies, Inc.
website:https://www.heliosense.com/
Contact:+86-592-5667290
Address:Xiamen Torch Hi-tech Zone Venture Weiye Building S506
website:http://www.afinechem.com
Contact:+86-571-85134551
Address:No. 206 Zhen Hua Road, Hangzhou 310030, Zhejiang, China
Contact:+49-9398-993127
Address:Untertorstr. 27
Doi:10.1016/j.tet.2004.03.056
(2004)Doi:10.1007/BF00486931
()Doi:10.1021/om960666v
(1996)Doi:10.1021/jo990575i
(1999)Doi:10.1016/S0957-4166(03)00580-9
(2003)Doi:10.1021/jo00826a017
(1970)
