Bioorganic and medicinal chemistry letters p. 69 - 74 (1999)
Update date:2022-07-30
Topics:
Shih, Chuan
Gossett, Lynn S.
Gruber, Joseph M.
Grossman, C. Sue
Andis, Sherri L.
et al.
Structure modification of the β-alanine region (fragment C) of the potent antimitotic agent cryptophycin was investigated. This includes: (1) introduction of substituents at the previously unsubstituted C7 position of the macrolide ring and (2) replacement of the (2R)-3-amino-2-methyl-propanoic acid (β-alanine) with various (l)-amino acids to give the corresponding 15-membered unnatural cryptophycin analogs.
View MoreHUNAN CHEMAPI BIOLOGICAL TECHNOLOGY CO.,LTD.
Contact:+86-186-02659358
Address:1004, building 3, Wanke Jinsemaitianyuan, 498 Guitang Road, Yuhua District, Changsha City, Hunan Province, China
Contact:86-511-85210668 0511-85210668, 85210818, 85210898
Address:Yihai Garden E-902,NO.99 Daxi RD., Zhenjiang Jiiangsu ,China
Xi'an yuanfar international trade company
website:https://www.yuanfarchemical.com
Contact:86-029-88745613 ext 828
Address:Floor19th ,B Building, Oak Block,No.36 South Fenghui Road, Dev. Zone of High-Tech Ind.,Xi’an, China
Shenzhen HwaGen Pharmaceutical Co., Ltd
website:http://www.rafflespt.com
Contact:+86-752-5538396
Address:Guangdong Huizhou China
Nanjing Ruizhi Industry & Technologh Co.，Ltd.
Contact:+86-25-86808110
Address:441-4-A5,NO.12 Longzang Avenue,Yuhuatai District,210039,Nanjing
Doi:10.1016/j.tet.2004.03.056
(2004)Doi:10.1007/BF00486931
()Doi:10.1021/om960666v
(1996)Doi:10.1021/jo990575i
(1999)Doi:10.1016/S0957-4166(03)00580-9
(2003)Doi:10.1021/jo00826a017
(1970)
