Solid-phase synthesis of phenolic steroids: Towards combinatorial libraries of estradiol derivatives

DOI: 10.1016/S0040-4039(98)02640-9

Source and publish data:

Tetrahedron Letters p. 1277 - 1280 (1999)

Update date:2022-08-02

Topics:

Authors:

Tremblay, Martin R.

Poirier, Donald

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Article abstract of DOI:10.1016/S0040-4039(98)02640-9

The 16β-(azidopropyl) derivative of estradiol (7) was synthesized and coupled to aminomethyl resin via a photolabile o-nitrobenzyl linker. Condensation of the corresponding iminophosphorane with activated acids successfully gave amides. Photocleavage resu

Full text of DOI:10.1016/S0040-4039(98)02640-9

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