The structural requirements for an inverse substrate for enzymatic peptide synthesis: Position isomers of guanidinonaphthyl esters as the acyl donor component

DOI: 10.1248/cpb.47.104

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 104 - 110 (1999)

Update date:2022-08-03

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Authors:

Sekizaki, Haruo

Itoh, Kunihiko

Toyota, Eiko

Tanizawa, Kazutaka

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Article abstract of DOI:10.1248/cpb.47.104

Four series of inverse substrates, position isomers of guanidinonaphthyl esters derived from N-(tert-butyloxycarbonyl)amino acid, were prepared as acyl donor components for trypsin-catalyzed peptide synthesis. The kinetic behavior of these synthetic inver

Full text of DOI:10.1248/cpb.47.104

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