4,4-Difluoro-1α,25-dihydroxyvitamin D3: Analog to probe A-ring conformation in vitamin D-receptor complex

DOI: 10.1016/S0040-4039(99)00030-1

Source and publish data:

Tetrahedron Letters p. 1697 - 1700 (1999)

Update date:2022-08-03

Topics:

Authors:

Shimizu, Masato

Iwasaki, Yukiko

Yamada, Sachiko

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Article abstract of DOI:10.1016/S0040-4039(99)00030-1

4,4-Difluoro-1α,25-dihydroxyvitamin D₃ was synthesized from ergosterol and analysis of its ¹⁹F NMR showed it to be a useful probe to analyze the receptor-bound A-ring conformation of vitamin D.

Full text of DOI:10.1016/S0040-4039(99)00030-1

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