Tetrahedron Letters p. 1819 - 1822 (1999)
Update date:2022-08-03
Topics:
Coldham, Iain
Fernandez, Joan-Carles
Snowden, David J.
Cyclizations of α-amino-organolithiums, derived by tin-lithium exchange, which proceed via a stereoselective two-electron process and totally regiospecific 5-exo-trig ring closure, have been extended to the preparation of the 7-azabicyclo[2.2.1]heptane ring system. Cyclization occurs from either the cis or the trans isomer of 5-allyl-2-tri-n-butylstannyl-N- benzylpyrrolidine to give only the exo product as a single diastereomer in isolated yields up to 83%.
View MoreLiaoyang Xinyou Chemical Products Co.,Ltd.
Contact:+86-419-5165433 13604191870
Address:Huishang Road6-1, Hongwei District, Liaoyang, Liaoning, China
Tianjin Pharmacn Medical Technology Co.,Ltd.
Contact:86-22-60122566ext.866(English),23359620
Address:Green Industrial Base, 6 Haitaifazhan Sixth Rd., Huayuan Industrial Area, Tianjin, 300384, China
Contact:+852 83038667
Address:Room 1502, 15th Floor, SPA Centre,53-55 Lockhart Road, Wanchai, Hong Kong
website:http://www.np-chem.com
Contact:0086-25-52346877
Address:199, Jian Ye Road, Nanjing, China
Rudong Zhenfeng Yiyang Chemical Co., Ltd.
Contact:0513-84573047
Address:South Fengli Town, Rudong County, Jiangsu Province, China
Doi:10.1007/BF01031792
()Doi:10.1016/0031-9422(80)83096-2
(1980)Doi:10.1016/S0040-4039(99)00233-6
(1999)Doi:10.1016/j.bmc.2018.07.004
(2018)Doi:10.1039/J19690000084
()Doi:10.1080/00397910701648769
(2008)
