
Bioorganic and Medicinal Chemistry Letters p. 323 - 326 (1999)
Update date:2022-08-05
Topics:
Perrier, Helene
Bayly, Christopher
Laliberte, France
Huang, Zheng
Rasori, Roberta
Robichaud, Annette
Girard, Yves
Macdonald, Dwight
The synthesis and in vitro activity of a series of substituted furans as a novel structural class of PDE4 inhibitors is described. Comparison of emetic threshold with known PDE4 inhibitors is presented.
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(2005)Doi:10.1039/a808422j
(1999)Doi:10.1021/ja2118267
(2012)Doi:10.1021/acs.jmedchem.7b01426
(2017)Doi:10.1002/cctc.201700179
(2017)Doi:10.1016/S0040-4039(99)00044-1
(1999)