Tetrahedron p. 3305 - 3316 (1999)
Update date:2022-07-29
Topics:
Corey
Li, Wei-Dong Z.
Nagamitsu, Tohru
Fenteany, Gabriel
The synthesis of analogs of the lactacystin-derived β-lactone (2) in which the substituents at C(5), C(7) and C(9) were systematically varied has led to a well defined structure-activity correlation for the highly selective inhibition of the mammalian 20 S proteasome.
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(1969)
