Bioorganic and Medicinal Chemistry Letters p. 1133 - 1138 (1998)
Update date:2022-08-04
Topics:
Ali, Syed M.
Tedford, Clark E.
Gregory, Rosilyn
Yates, Stephen L.
Phillips, James G.
New histamine H3 receptor antagonists were developed using an acetylene moiety as a replacement for the amide-oxime functionality of verongamine 5. Optimization of receptor binding was performed by following aliphatic Topliss tree guidelines. These new H3 ligands demonstrate excellent blood-brain barrier penetration.
View MoreShandong Shouguang Songchuan Industrial Additives Co.,Ltd
Contact:+86-536-8566856
Address:Shouguang,Shandong,China
website:http://www.vanzpharm.com/en/index.html
Contact:86-27-84492310
Address:FANHU INDUSTRY PARK
JIANGSU GRAND XINYI PHARMACEUTICAL CO.,LTD
website:http://www.xypharm.com/
Contact:+86-515-84383317
Address:Chenli Road,Costal Chemical Area Binhai,Yancheng, Jiangsu,China
website:http://www.truewingroup.com
Contact:86-311-66699812
Address:NO.600 ZHONGSHAN EAST ROAD SHIJIAZHUANG
Changzhou Xuanming Chemical Co., Ltd.
Contact:86 0519 85525329
Address:China Town, Xinbei, Changzhou, Jiangsu Room 6019
Doi:10.1021/jo981487l
(1999)Doi:10.1021/jm0301787
(2003)Doi:10.1016/j.bmc.2016.11.037
(2017)Doi:10.1007/BF00515577
(1991)Doi:10.1021/acs.jmedchem.8b00613
(2018)Doi:10.1021/ja00837a028
(1975)
