Metacyclophanes and Related Compounds. 14. Preparation of 8,16-Difluorometacyclophane

DOI: 10.1021/jo00216a026

Source and publish data:

Journal of Organic Chemistry p. 2939 - 2942 (1985)

Update date:2022-08-04

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Authors:

Tashiro, Masashi

Yamato, Takehiko

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Article abstract of DOI:10.1021/jo00216a026

Although preparation of 8,16-difluoro-, 8,16-dichloro-, and 8,16-dibromo<2.2>metacyclophanes was attempted, only 8,16-difluoro<2.2>metacyclophane was obtained from fluorobenzene in seven steps by using a tert-butyl group as a positional protective function.

Full text of DOI:10.1021/jo00216a026

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