Synthesis of new 1H-imidazoles via reactions of 3(,5)-(di)chloro-2H- 1,4-(benz)oxazin-2-ones with α-aminoketones

Article abstract of DOI:10.1016/S0040-4020(99)00087-3

3,5-Dichloro-2H-1,4-oxazin-2-ones 1 and 3-chloro-2H-1,4-benzoxazin-2- ones 2 react with α-aminoketones to yield bi- and tricyclic imidazo-fused intermediates via an intramolecular cyclisation reaction. Reaction of these lactone intermediates with various