Heterocycles p. 189 - 198 (2003)
Update date:2022-08-02
Topics:
Burger, Klaus
Lange, Torsten
Rudolph, Martin
A highly efficient method for regiospecific α-functionalization of aspartic acid is described. Key step is the synthesis of a N-protected and regioselectively α-carboxy-activated heterocyclic intermediate from aspartic acid and hexafluoroacetone. The new strategy offers i.a. a two step access to the sweetener Aspartame and to libraries of aspartame analogues.
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Doi:10.1016/S0040-4039(01)92421-9
(1981)Doi:10.3987/COM-03-S(P)48
(2004)Doi:10.1002/mrc.1270130512
(1980)Doi:10.1007/BF00922874
()Doi:10.1016/S0040-4039(00)80155-0
(1988)Doi:10.1039/c7gc00192d
(2017)