RSC Advances p. 6636 - 6642 (2019)
Update date:2022-07-29
Topics:
Aksenov, Alexander V.
Khamraev, Vladislav
Aksenov, Nicolai A.
Kirilov, Nikita K.
Domenyuk, Dmitriy A.
Zelensky, Vladimir A.
Rubin, Michael
A novel methodology for general and chemoselective preparation of non-symmetric 1,3,4-oxadiazoles is developed. This unusual reaction proceeds via polyphosphoric acid-assisted activation of nitroalkanes towards nucleophilic attack with acylhydrazides.
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