Synthesis and antibacterial activity of S-substituted 2-thioquinazolin-4(3H)-ones

DOI: 10.1007/BF02974939

Source and publish data:

Pharmaceutical Chemistry Journal p. 642 - 643 (1999)

Update date:2022-08-05

Topics: Synthesis   Column chromatography   Melting point   Yield   Recrystallization   Nucleophilic substitution   Antibacterial activity   TLC (thin-layer chromatography)   HPLC (high-performance liquid chromatography)   Thioether   Zone of Inhibition   Structure-Activity Relationship (SAR)   Antimicrobial assay   Quinazolinone   Solvent system   Spectroscopy (NMR, IR, MS)   MIC (Minimum Inhibitory Concentration)   Gram-positive/Gram-negative bacteria  

Authors:

Krasovskii

Bulgakov

Chumakova

Krasovskii

Dyachenko

Bokun

Kravchenko

Demchenko