Synthesis and antihypertensive activity of some quinazolinone derivatives

DOI: 10.1002/ardp.19853180605

Source and publish data:

Archiv der Pharmazie p. 502 - 505 (1985)

Update date:2022-08-05

Topics: Synthesis Derivatives antihypertensive Quinazolinone

Authors:

Liu Liu

Hsu Hsu

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Article abstract of DOI:10.1002/ardp.19853180605

The fused 4(3H)-quinazolinone derivatives 4a-e were synthesized by treating 2-thioxo-1H,3H-quinazolin-4-one with halides. A preliminary pharmacological evaluation revealed that the compounds, 4b-4d act as antihypertensives in anesthetized rats at i.v. dos

Full text of DOI:10.1002/ardp.19853180605

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