
Archiv der Pharmazie p. 502 - 505 (1985)
Update date:2022-08-05
Topics: Synthesis Derivatives antihypertensive Quinazolinone
Liu
Hsu
The fused 4(3H)-quinazolinone derivatives 4a-e were synthesized by treating 2-thioxo-1H,3H-quinazolin-4-one with halides. A preliminary pharmacological evaluation revealed that the compounds, 4b-4d act as antihypertensives in anesthetized rats at i.v. dos
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