Journal of Organic Chemistry p. 309 - 317 (2016)
Update date:2022-09-26
Topics:
Shen, Zi-Chao
Yang, Pan
Tang, Yu
A fast catalytic synthesis of multisubstituted quinazolines from readily available amidines via visible light-mediated oxidative C(sp3)-C(sp2) bond formation has been established. This reaction is a metal-free oxidative coupling catalyzed by a photoredox organocatalyst. The protocol features low catalyst loading (1 mol %).
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