Synthesis of C-glycosides via radical cyclization reactions with a vinylsilyl tether. Control of the reaction course by a change in the conformation of the pyranose ring due to steric repulsion between adjacent bulky protecting groups

Article abstract of DOI:10.1016/S0040-4039(99)01026-6

A stereoselective method for introducing a C2-unit at the 1α- and 1β- postions of D-glucose and D-mannose, respectively, via a radical cyclization reaction with vinylsilyl group as a temporary connecting tether, was developed. The radical cyclization of D