Pharmaceutical Chemistry Journal p. 146 - 147 (1995)
Update date:2022-08-02
Topics:
Alekseeva, N. N.
Koikov, L. N.
3-(N-morpholino)-3-cyanoquinuclidine has been shown to form only 1-methyl-3-(N-morpholino)-3-cyanoquinuclidinium iodide or 1-benzyl-3-(N-morpholino)-3-cyanoquinuclidinium chloride when treated with iodomethane (1:1 or 1:2.3) or benzene chloride (1:1), respectively.The direction of quarternization is determined using 1H NMR spectroscopy.
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