Chemical and Pharmaceutical Bulletin p. 1288 - 1296 (1999)
Update date:2022-08-04
Topics:
Zheng, Bao-Zhong
Maeda, Hiroshi
Mori, Michiko
Kusaka, Shin-Ichi
Yonemitsu, Osamu
Matsushima, Tomohiro
Nakajima, Noriyuki
Uenishi, Jun-Ichi
An efficient and stereoselective synthesis of the C13 - C23 part (8) was achieved starting from methyl (R) - and (S)-3-hydroxy-2-methylpropionates (9) via coupling of the C13 - C17 aldehyde (6), prepared by Evans asymmetric aldol reaction, with the C18 - C21 iodoalkene (5b) by taking advantage of the 3,4-dimethoxybenzyl protecting group.
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(1954)Doi:10.1039/j39690001886
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(1955)Doi:10.1021/ic990328x
(1999)Doi:10.1002/hlca.19690520626
(1969)Doi:10.1021/acs.jmedchem.7b01666
(2018)
