Intramolecular, Site-Selective, Iodine-Mediated, Amination of Unactivated (sp3)C-H Bonds for the Synthesis of Indoline Derivatives

DOI: 10.1021/acs.orglett.7b00846

Source and publish data:

Organic Letters p. 2793 - 2796 (2017)

Update date:2022-08-03

Topics:

Authors:

Long, Jinguo

Cao, Xin

Zhu, Longzhi

Qiu, Renhua

Au, Chak-Tong

Yin, Shuang-Feng

Iwasaki, Takanori

Kambe, Nobuaki

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Article abstract of DOI:10.1021/acs.orglett.7b00846

The Iodine-mediated oxidative intramolecular amination of anilines via cleavage of unactivated (sp³)C-H and N-H bonds for the production of indolines is described. This transition-metal-free approach provides a straightforward strategy for prod

Full text of DOI:10.1021/acs.orglett.7b00846

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