New application of the Julia olefination for the synthesis of Tyr-Gly E-alkene and carba isostere pseudopeptides

DOI: 10.1016/S0040-4039(99)01139-9

Source and publish data:

Tetrahedron Letters p. 5705 - 5707 (1999)

Update date:2022-08-03

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Authors:

Charrier, Cecile

Ettouati, Laurent

Paris, Joelle

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Article abstract of DOI:10.1016/S0040-4039(99)01139-9

A new application of the Julia olefination to the synthesis of TyrΨ[E-CH=CH]Gly and TyrΨ[CH₂CH₂]Gly pseudopeptides is described via condensation of tertiobutyl bromoacetate on tyrosine-derived β-ketosulfone and subsequent reductive desulfonation.

Full text of DOI:10.1016/S0040-4039(99)01139-9

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