Design and synthesis of amidino-tyrosine derivatives as non-peptide fibrinogen receptor antagonists

DOI: 10.1016/S0960-894X(99)00308-X

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1933 - 1936 (1999)

Update date:2022-08-04

Topics:

Authors:

Xu, Tian-Lin

Jiang, Xun-Tian

Hua, Wei-Yi

Ni, Pei-Zhou

Pei, Yong-Mei

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(99)00308-X

The design, synthesis and antiaggregation activity of amidino-tyrosine derivatives based on Arg-Gly-Asp (RGD) tripepride sequence as non-peptide fibrinogen receptor antagonists is described. Optimization of the spacer and the substituent at the C-terminal is reported.

Full text of DOI:10.1016/S0960-894X(99)00308-X

Products guided by the article

Product name:3-(4-hydroxy-phenyl)-2-(2-o-tolyloxy-acetylamino)-propionic acid methyl ester

Cas No:245428-30-2

R&D Labs maybe for 245428-30-2

shanghai payne pharm co.,ltd.

Contact:+86-021-58123769

Address:No.780 of Cailun Road,Zhangjiang Hi-tech Park,Pudong,Shanghai
SAGECHEM LIMITED

website:http://www.sagechem.com

Contact:+86-571-86818502

Address:Room C1301, New Youth Plaza, 8 Jia Shan Road, Hangzhou, China
Zipont chem(wuhan）Tech co.，Ltd

Contact:+86-27-87587198

Address:wuhan
Hawks Chemical

Contact:+44 (0)161 367 9441

Address:
JIAXING SUNS INTERNATIONAL TRADE CO LTD

Contact:18367306858

Address:No.123,Huixin Avenue,Huimin Dist

Relevant to this article

Synthesis of 4-substituted carbocyclic 2,3-dideoxy-3-C-hydroxymethyl nucleoside analogues as potential anti-viral agents

Doi:10.1016/S0040-4020(99)00591-8
(1999)
Asymmetric synthesis of 3-amino-2-hydroxy-4-phenylbutanoate

Doi:10.1016/S0957-4166(99)00249-9
(1999)
Copper(I) complexes with a proximal aromatic ring: Novel copper-indole bonding

Doi:10.1002/(sici)1521-3773(19990816)38:16<2401::aid-anie2401>3.0.co;2-v
(1999)
Direct stereo- and enantiocontrolled synthesis of vicinal stereogenic quaternary carbon centers. Total syntheses of meso- and (-)-chimonanthine and (+)-calycanthine [4]

Doi:10.1021/ja991714g
(1999)
14-Electron four-coordinate Ru(II) carbyl complexes and their five-coordinate precursors: Synthesis, double agostic interactions, and reactivity

Doi:10.1021/ja990621w
(1999)
Allosteric modulation of the adenosine A₁ receptor. Synthesis and biological evaluation of novel 2-amino-3-benzoylthiophenes as allosteric enhancers of agonist binding

Doi:10.1021/jm991051d
(1999)

Article Doi