
Bioorganic and Medicinal Chemistry Letters p. 1933 - 1936 (1999)
Update date:2022-08-04
Topics:
Xu, Tian-Lin
Jiang, Xun-Tian
Hua, Wei-Yi
Ni, Pei-Zhou
Pei, Yong-Mei
The design, synthesis and antiaggregation activity of amidino-tyrosine derivatives based on Arg-Gly-Asp (RGD) tripepride sequence as non-peptide fibrinogen receptor antagonists is described. Optimization of the spacer and the substituent at the C-terminal is reported.
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Doi:10.1016/S0040-4020(99)00591-8
(1999)Doi:10.1016/S0957-4166(99)00249-9
(1999)Doi:10.1002/(sici)1521-3773(19990816)38:16<2401::aid-anie2401>3.0.co;2-v
(1999)Doi:10.1021/ja991714g
(1999)Doi:10.1021/ja990621w
(1999)Doi:10.1021/jm991051d
(1999)