Synthesis of 4-substituted carbocyclic 2,3-dideoxy-3-C-hydroxymethyl nucleoside analogues as potential anti-viral agents

DOI: 10.1016/S0040-4020(99)00591-8

Source and publish data:

Tetrahedron p. 10761 - 10770 (1999)

Update date:2022-08-04

Topics:

Authors:

Wachtmeister, Johanna

Muehlman, Anna

Classon, Bjoern

Samuelsson, Bertil

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Article abstract of DOI:10.1016/S0040-4020(99)00591-8

The synthesis of two carbocyclic guanosine analogues with an electronegative fluoro or hydroxy substituent in the 4-position is described. The cyclopentanols 17a and 18 were synthesized from enantiomerically pure 3S,4S-bis(hydroxymethyl)cyclopentanone eth

Full text of DOI:10.1016/S0040-4020(99)00591-8

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